The Pilgrims were too strong for their fellow strugglers at Croft Park - with Burrow's 19th minute header and McLintock's 44th minute drive handing United a commanding half-time lead.
Chadwick doubled the lead nine minutes after the break - with Wright adding a fourth in stoppage time after Troy Chiabi had briefly reduced the arrears for the hosts.
McLintock and Lirak Hasani were restored to the starting XI ahead of kick-off and United, resplendent in pink once again, started well.
Blyth did threaten for the first time with Chiabi heading wide from a Main cross, but United got into their groove and Alex Mitchell saved well to deny McLintock from distance.
The Pilgrims took the lead when Chadwick delivered a quality ball from the right and BURROW got up at the back post to dispatch a firm header beyond Mitchell into the bottom corner.
Chadwick sent an audacious chip narrowly off target, while Gregory did well to deny Chiabi from outside the box.
United doubled their lead a minute before half-time when Chadwick's corner was only partially cleared and McLINTOCK crashed home a terrific volley from 20 yards.
Luke Shiels was denied by a Nicky Deverdics goalline clearance at the start of the second half, but United were soon three goals to the good when CHADWICK weaved infield to beat Mitchell with a fine effort in the 54th minute.
Mitchell repelled Tom Nixon, while Gregory made a super save to keep out Jordan Hickey's firm drive.
CHIABI did cut the deficit with four minutes to play with a fine, rising finish from 18 yards - but WRIGHT had the last laugh by rifling home United's fourth in the third minute of stoppage time.
Blyth Spartans (4-3-3): Alex Mitchell; Rhys Evans, Toby Lees (Matty Elsdon 72), Finn Cousin-Dawson, Curtis Round; Will McGowan, Jordan Hickey, Nicky Deverdics; Troy Chiabi, Cedric Main (JJ O'Donnell 59), Michael Spellman. Subs (not used): Michael Richardson, Josh Gillies, Matty Dopson.
Boston (4-1-2-1-2): Cameron Gregory; Tom Nixon, Luke Shiels, Ben Pollock, Ethan Sephton; Tom Platt; Zak Mills, Lirak Hasani; Sam McLintock (Luther Munakandafa 82); Jordan Burrow (Tre Mitford 73), Billy Chadwick (Jake Wright 73). Subs (not used): Keenan Ferguson, Will Atkinson.
Referee: Paul Cooper.
Attendance: 838.
PIC: Ian Kelsey.