The Pilgrims head to Mill Farm in pursuit of a positive result to bounce back from the disappointment of their narrow 1-0 defeat at FC Halifax Town on Saturday.
The Coasters, meanwhile, were drawing 1-1 against Dagenham & Redbridge on Saturday to stretch their points advantage over the Pilgrims to nine ahead of Tuesday's clash.
Fylde were 2-1 victors at the Jakemans Community Stadium earlier in the season, with United having led 1-0 at half-time through Pemi Aderoju's only league goal for the Pilgrims.
United boss Graham Coughlan will check on the fitness of midfielder Martin Woods, who limped out of Saturday's defeat at The Shay.
Long-term absentees Michael Bostwick, Mitch Roberts, Dan Adshead and Oisin Gallagher remain sidelined.
LIVE COVERAGE
The match will be shown live on National League TV.
Elsewhere, BBC Radio Lincolnshire full-match commentary, courtesy of Rob Makepeace and Tom Bennett, is available.
X updates will be available via @bostonunited throughout the evening.
TICKETS
Tickets for away supporters can be purchased here.
KIT WATCH
United will be wearing their third kit of raspberry and rhodamine red.
PIC: Chris Bray.